Can I host 1 call with 2 different groups at the same time?
You would need two different accounts for this.
One account comes with one conference room so you won’t be able to have two groups simultaneously.
I may have read this question differently.
if you are hosting 1 meeting, but several different “groups” of people are joining from different locations, then yes you can host different groups (think of it as you are on stage, but there are a couple of jumbotrons for you to be seen in the audience).
But, if your question is to host 2 different meetings at the same time (different topics, and audience), you’ll need more than one account, you’ll need to be Michael Keaton in the movie Multiplicity.